Pet Stem Cell Therapy

We all know the importance of Adopt Dont Shop! and rescuing furry friends that are in shelters. We have many incredible shelters around Maine with high volume, allowing our residents to have ample opportunities and options for bringing a pet home in the most benevolent way.

If youve been in the market for a new four-legged friend, Maine now has 61 new cats and dogs that just got rescued from Puerto Rico and are ready to be adopted!!

Animal Refuge League of Greater Portland recently sent over volunteers on a Freedom Flight with nonprofit Wings of Rescue to rescue more than 300 cats and dogs from Puerto Rico. Of those animals, 61 have been brought to Maine with the rest being housed in shelters in New York.

As the Refuge shared with News Center Maine, a lot of locations where the pets were rescued are still damaged by Hurricane Maria and there are more than 500,000 stray dogs on the island right now due to most of them not being fixed.

The most touching part was when the director of community engagement shared with the outlet that when they first met the animals, they were really timid, shy, and scared; In just a matter of two days, they watched the animals get comfortable in the feeling of safety and start to play, run around and snuggle.

There are now even more animals to choose from to save from shelters here in Maine that meet your needs. You can visit the Animal Refuge League in person in Westbrook or visit their website to learn more about how to adopt or get involved.

Regardless, you should definitely follow their Instagram so you can see the adorable pictures of the rescued furry friends!! Plus, sharing the content can help these guys get adopted.

KEEP LOOKING: See What 50 of America's Most 'Pupular' Dog Breeds Look Like as Puppies

To prepare yourself for a potential incident, always keep your vet's phone number handy, along with an after-hours clinic you can call in an emergency. The ASPCA Animal Poison Control Center also has a hotline you can call at (888) 426-4435 for advice.

Even with all of these resources, however, the best cure for food poisoning is preventing it in the first place. To give you an idea of what human foods can be dangerous, Stacker has put together a slideshow of 30 common foods to avoid. Take a look to see if there are any that surprise you.

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More Pets up for Adoption in Maine After Animal Refuge Rescue - WJBQ

Changes of macrophage and CD4+ T cell in inflammatory response in type 1 diabetic mice | Scientific Reports – Nature.com

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Changes of macrophage and CD4+ T cell in inflammatory response in type 1 diabetic mice | Scientific Reports - Nature.com

Are Students In NJ Going To Be Allowed To Identify As Cats? – 943thepoint.com

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Are Students In NJ Going To Be Allowed To Identify As Cats? - 943thepoint.com

OK, I can't name names for PR sake, buta close friend of mine is a manager at a major company and one of his employees recentlyannounced that they identify as a cat. You read that right, she feels like a feline trapped in a woman's body. Now, this is uncharted territory for this manager friend of mine and after looking into it, he has to comply with reasonable accommodations and full acceptance so long as it does not interfere with her tasks at work. In the words of the great Pauly D, "what a country".

Now, I just read in the Herald Sunthat this cat identity thing it is not just us, there's a studentin Australia that says she identifies as a cat andher school has to deal with it.

Kids have to find themselves right? We all try on different identities to figure out who we are and what we like. I knew someone who was a cowboy one year and the next year he came back into school with droopy jeans and rapper swag. I did it too, I was a dancer in high school and I was mad that I was not on the show Fame so I protested by wearing ballet slippers as shoes (Leroy would have understood me). Anyway, Weve all been there but where do we draw the line? There are always people pushing the proverbial envelope and this one is really over the top.

The student in Australia I was telling you about declared that she identifies as a cat and the school is allowing her to live her truth. The school actually granted her the right to be non-verbal and to act feline. The school'sonly boundary? Her identitycant be a distraction to the other students learning.Are you kidding me? Im distracted and Im not even in the room.

I mean, how far does this thing go? Are they going to put a litter box in the corner of the classroom? The school says that they have no precedent for this kind of identity claim and they are figuringit out as it comes. They did admit that as more students come out as animals they will have to draft some rules. WTH?

Another school in Brisbane allowed multiple students to walk on all fours and cut holes in their uniforms to make room for their tails. Im sorry, we are all different, but the one thing we do have in common is that we are all human.

Is this going to fly in New Jersey schools? Are there any teachers dealing with this locally? Would you want your school to allow all of this? Email me shannon.holly@townsquaremedia.com

By the way, I don't want to ignore man's best friend with all this cat talk. Be careful you don't feed your dog any of these human foods or you can make them super sick!

Hey Illinois, There Are 5 Foods You Need To Throw Out After Their Expiration Dates – q985online.com

Grocery prices have skyrocketed over the last few years and while you're looking to save money you need to be careful. There are a few things you definitely do not want to eat after their expiration date.

When you were a child did you ever reach into the fridge for something and notice the item was past its expiration date? I feel like the famous line from parents and grandparents was, "does it smell ok?" Is thisreally the best idea when it comes to food that might need to be tossed?

Akdemirhk; ThinkStock

If you spot mold on it, that's probably a good indicator if the scent isn't enough. The visible text could be another sign but not always. When I was a kid I was always getting in trouble for tossing out french onion dip. In my little mind, that water in the container meant I should throwit away. It wasn't until into my 20s that I accepted it just needed to be stirred.

Do you know which items in your fridge should be thrown away when their expiration date hits? You might be surprised by this.

Soft cheeses like Velveeta, feta, brie, blue, and queso fresco need to be given the ol' heave-ho. This is especially important if they're made with unpasteurized milk.)

A variety of packages of ground beef at the supermarket

Whole meats may be OK to keep after their expiration dates but ground meats are not, they're more likely to have contamination.

Believe it or not, chicken breasts come from the store with a whole lot of bacteria. Once that expiration date is passed, toss it. Alfalfa sprouts and eggs also made the list.

[h/t Prevention]

See the article here:
Hey Illinois, There Are 5 Foods You Need To Throw Out After Their Expiration Dates - q985online.com

Recruitment opens for Phase II trial in prostate cancer with Cu-64 SAR-Bombesin in the US – Tullahoma News and Guardian

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‘Doctors are best in the world’ – Dad with two cancers walks to thank The Christie – Knutsford Guardian

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'Doctors are best in the world' - Dad with two cancers walks to thank The Christie - Knutsford Guardian

A COURAGEOUS dad battling two cancers is taking on a 10k charity walk round Tatton Park.

Dad-of-two Jason Wilcox wants to thank The Christie for all their care and treatment.

The 46-year-old will be joining the Walk of Hope on Saturday, September 17, wife Jen and children Ella, 12, and Harry, nine, Families, friends and individuals will team up to support the hospital.

Lantern decorating, face painting and live music will entertain walkers before they set off.

Jason,was diagnosed with Non-Hodgkin Lymphoma in December 2019 after a tennis ball sized lump appeared on his neck.

As he was being treated for that, a routine PET scan in May 2022 found a rare neuroendocrine tumour.

READ >Alderley Edge woman banned from driving after 'repeat offending'

Following treatment at The Christie, the Non-Hodgkin Lymphoma is now in remission, but treatment for the neuroendocrine tumour is continuing.

Jason Wilcox wants to thank staff at The Christie for all their treatment and care

Jason started chemotherapy but when that didnt work he was referred to The Christie in January 2021 for a highly specialist treatment called CAR-T therapy.

This removing immune cells called T-cells through a sample of the patient's blood.

They are then reprogrammed in a laboratory to create cells that are genetically coded to recognise and destroy the patient's cancer cells. Jason was an inpatient at The Christie for five weeks during this treatment.

In September 2021, he joined a clinical trial for the drug epcoritamab.

Jason is currently waiting for a stem cell transplant.

This was delayed when he picked up a continuous cough after having Covid in July and doctors are currently investigating this before the stem cell transplant can go ahead.

Since July 2022, Jason has also been having hormone therapy injections to hopefully prevent his neuroendocrine tumour from getting bigger or spreading.

The plan is to have this tumour surgically removed once he has recovered from the stem cell transplant.

Jason said: I have always felt like the staff all really care about me. Everyone is friendly and approachable, during the good times and bad. It is good to know that Im in the best place with all the resources under the same roof.

The doctors and nurses are some of the best in the world and I couldnt ask for more.

Wife Jen, 46, said: Jason has spent the last 20 months receiving the very best care and support from The Christie.

His team have been a tremendous support and we have felt so well looked after.

The overwhelming feeling you get is they care and they want to do their best for every single patient.

Unless you have seen that up close you dont realise how much The Christie does for people with cancer and how much they rely on the fundraising.

We like to get out and about as much as possible as a family and have a dog who keeps us active, however, Jason isnt able to walk as far as he used to due to all the treatment hes had.

After everything that has been done for us, we wanted to do something as a family to support The Christie and The Walk of Hope seemed like an ideal opportunity.

Its family-friendly and sounds like itll be a wonderful evening whilst raising money for a very worthy cause.

Its unlikely that Jason will be able to complete the walk, however, he will be there to cheer us on.

Abbie Wicks, sporting events officer from The Christie charity said: We are very grateful to Jason, Jen, Ella and Harry for signing up to the Walk of Hope this year and for the fundraising they have already done to support our cancer patients.

The Walk of Hope is one of our most emotional and inspirational events each year with so many people walking in memory, in support or in hope.

Before the walk begins, we have lantern decorating, face painting and live entertainment.

This is followed by a peaceful dove release to start the walk. After taking in the stunning scenery of Tatton Park, the evening will finish with a chorus of live music.

To sign up for the Walk of Hope visit christie.nhs.uk/the-christie-charity/get-involved/fundraise/events/events-calendar/walk-of-hope

Regenerative Therapies Market 2018 By Emerging Trends, Industry Share, Regional Overview and SWOT Analysis till 2026 – Digital Journal

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Regenerative Therapies Market 2018 By Emerging Trends, Industry Share, Regional Overview and SWOT Analysis till 2026 - Digital Journal

Regenerative Therapies Market

The use of certain kinds of cells or cell products for sick organs or tissues is known as regenerative therapy. This procedure might eventually aid in the restoration of function of tissues and organs. It also includes the prospect of developing tissues and organs in the lab and then implanting them securely when the body is unable to mend itself. The lack of treatment requirements is the primary growth factor for the global regenerative therapies market. The formulation and acceptance of supporting legislation and policy measures are likely to boost government assistance for the treatment of numerous diseases across the world. It also comprises significant expenditures in regenerative medicines, such as commercialization centers, the establishment of research networks, centers of excellence and manufacturing infrastructure.

In addition to that, rising demand for stem cell and tissue-cell research methods, as well as the items developed using them is likely to propel the global regenerative therapies market forward in the years to come. These products are utilized to treat a wide variety of chronic diseases that do not have permanent cure. Nevertheless, a trend in the market has been seen in which corporations are shifting away from making synthetic pharmaceuticals and toward exploring potential for producing medications from an individuals own stem cells and tissues. The global regenerative therapies market, which is still in its early stages of commercialization, offers attractive investment possibilities provided by the private firms, regional governing bodies, and government bodies.

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Global Regenerative Therapies Market: Overview

The demand for regenerative therapies is growing markedly as regenerative medicines are considered promising to treat complex degenerative diseases. Growing government support to provide better and effective treatment for chronic disorders has also created growth opportunities for this market. Moreover, growing investment by private and government organizations that support research and development of stem cell and regenerative medicine, thus, fueling the markets growth. In addition, rising investment in research networks, manufacturing infrastructure, building commercialization centers, and centers for excellence are means indirectly supporting the growth of the regenerative therapies market at the global level.

The global regenerative therapies market is categorized on the basis of type of tissue, application, and end user. Based on end-user, the global market could be segmented into ambulatory surgical centers, educational institutes, and hospitals.

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The report elaborates on the key factors that are responsible for the growth of the regenerative therapies market. These factors include drivers, restraints, trends, and opportunities. Moreover, it provides an in-depth analysis of geography and on the key segments that are derived through factual knowledge.

Global Regenerative Therapies Market: Trends and Opportunities

The demand for regenerative therapies is expected to increase in the near future due to long-term effectiveness and safer results provided by it. Globally, people nowadays want fast treatment has also triggered the demand for regenerative therapies. The recent trend prevalent is by producing medicines with the help of tissues and stem cells derived from human body, this is expected to provide a fillip to the market. Moreover, growing investment from governments and private firms is likely to open new avenues for growth for manufacturers. Adding to it, manufacturers are shifting from synthetic drugs manufacturing to regenerative therapy drugs. Furthermore, the regenerative therapies are also used in treating ocular, neurological, autoimmune, orthopedic, rare and cardiovascular disorders.

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Global Regenerative Therapies Market: Geographic Analysis

The global regenerative therapies market is expected to find North America taking the drivers seat in terms of growth in the forthcoming years. Favorable government policies for regenerative therapies in Canada and in the United States is supporting the growth in this market. In addition to that, development of new clinical infrastructure and high penetration of tissue banks could likely increase the demand in the regenerative therapies market in the near future.

Asia Pacific is offering lucrative growth opportunities and is expected to rise at a healthy CAGR over the forecast tenure. Growing investment in healthcare research in the emerging economies is observed as a crucial driver for this market. On the other hand, the Middle East and Africa are expected to witness sluggish growth due to lack of suitable regulations in the region.

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Global Regenerative Therapies Market: Competitive Landscape

The vendor landscape presented in the report gives a complete information about the various players operating in the regenerative therapies market at the global level. To mention some of the prominent players in the market are Astellas Pharma U.S., Organovo Holdings Inc., Inc., Nuo Therapeutics, Inc., Acelity L.P. Inc., and Mesoblast Ltd. to meet the demand for unmet clinical needs these players are focusing on developing innovative novel therapies. They are also investing heavily in mergers and acquisitions to expand their geographical reach. This will further aid the companies to get a stronghold in the global market.

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Dad with ‘tennis ball’ sized lump finds out he has two cancers – Liverpool Echo

A dad who found a "tennis ball sized lump" on his neck found out he had two life-threatening cancers at the same time.

In 2019, Jason Wilcox, 46, went for tests at Southport Hospital following a large lump that appeared on his neck. He was soon given the diagnosis of Non-Hodgkin Lymphoma, a rare cancer that develops in the lymphatic system.

But as he was being treated for that, three years later in May 2022, a routine PET scan discovered he had a rare neuroendocrine tumour, the Manchester Evening News reports. Following treatment at the Christie, the Assistant Manager at Howdens Joinery is now in remission for the Non-Hodgkin Lymphoma, but is continuing treatment for the neuroendocrine tumour.

READ MORE: Ryanair air hostess fighting for life after being hit by car

Jason started chemotherapy at Southport and Ormskirk Hospital but was soon referred to The Christie Hospital in January 2021 for a highly specialist treatment called CAR-T therapy, where he remained as an inpatient for five-weeks. This treatment involves removing immune cells called T-cells through a sample of the patient's blood and reprogrammed.

In September that year, the dad battling two cancers joined a clinical trial for the drug epcoritamab. He is now hoping to have a stem cell transplant, which was delayed when Jason developed a cough after having covid in July.

The Southport dad said: "I have always felt like the staff all really care about me. Everyone is friendly and approachable, during the good times and bad. It is good to know that Im in the best place with all the resources under the same roof. The doctors and nurses are some of the best in the world and I couldnt ask for more."

Since July 2022, Jason has also been having hormone therapy injections once a month to hopefully prevent his neuroendocrine tumour from getting bigger or spreading. The plan is to have this tumour surgically removed once he has recovered from the stem cell transplant.

But the family, including wife Jen, and their two children Ella, 12, and Harry, nine, will be taking on a 10k walk to raise funds for the Manchester cancer treatment centre at Tatton Park n September 17. More information about the The Walk of Hope and how to get involved can be found here.

Wife of 13-years Jen added: "Jason has spent the last 20 months receiving the very best care and support from The Christie. His team have been a tremendous support and we have felt so well looked after.

"The overwhelming feeling you get is they care, and they want to do their best for every single patient. But unless you have seen that up close you dont realise how much The Christie does for people with cancer and how much they rely on the fundraising that The Christie charity does.

"We like to get out and about as much as possible as a family and have a dog who keeps us active, however, Jason isnt able to walk as far as he used to due to all the treatment hes had.

"After everything that has been done for us, we wanted to do something as a family to support The Christie and The Walk of Hope seemed like an ideal opportunity. Its family-friendly and sounds like itll be a wonderful evening whilst raising money for a very worthy cause. Its unlikely that Jason will be able to complete the walk, however, he will be there to cheer us on."

Abbie Wicks Sporting Events Officer from The Christie charity said: "We are very grateful to Jason, Jen, Ella and Harry for signing up to the Walk of Hope this year and for the fundraising they have already done to support our cancer patients. The Walk of Hope is one of our most emotional and inspirational events each year with so many people walking in memory, walking in support or walking in hope.

"Before the walk begins, we have lantern decorating, face painting and live entertainment. This is followed by a peaceful dove release to start the walk. After taking in the stunning scenery of Tatton Park, the evening will finish with a chorus of live music."

Scientists use stem cells to create synthetic mouse embryos

Scientists have created synthetic mouse embryos from stem cells without a dads sperm or a moms egg or womb.

The lab-created embryos mirror a natural mouse embryo up to 8 days after fertilization, containing the same structures, including one like a beating heart.

In the near term, researchers hope to use these so-called embryoids to better understand early stages of development and study mechanisms behind disease without the need for as many lab animals. The feat could also lay the foundation for creating synthetic human embryos for research in the future.

We are undoubtedly facing a new technological revolution, still very inefficient but with enormous potential, said Llus Montoliu, a research professor at the National Biotechnology Centre in Spain who is not part of the research. It is reminiscent of such spectacular scientific advances as the birth of Dolly the sheep and others.

A study published Thursday in thejournal Nature, by Magdalena Zernicka-Goetz at the California Institute of Technology and her colleagues, was the latest to describe the synthetic mouse embryos. A similar study, by Jacob Hanna at the Weizmann Institute of Science in Israel and his colleagues, waspublished earlier this monthin the journal Cell. Hanna was also a coauthor on the Nature paper.

Zernicka-Goetz, an expert in stem cell biology, said one reason to study the early stages of development is to get more insight into why the majority of human pregnancies are lost at an early stage and embryos created for in vitro fertilization fail to implant and develop in up to 70% of cases. Studying natural development is difficult for many reasons, she said, including the fact that very few human embryos are donated for research and scientists face ethical constraints.

Building embryo models is an alternative way to study these issues.

To create the synthetic embryos, or embryoids, described in the Nature paper, scientists combined embryonic stem cells and two other types of stem cells all from mice. They did this in the lab, using a particular type of dish that allowed the three types of cells to come together. While the embryoids they created werent all perfect, Zernicka-Goetz said, the best ones were indistinguishable from natural mouse embryos. Besides the heart-like structure, they also develop head-like structures.

This is really the first model that allows you to study brain development in the context of the whole developing mouse embryo, she said.

The roots of this work go back decades, and both Zernicka-Goetz and Hanna said their groups were working on this line of research for many years. Zernicka-Goetz said her group submitted its study to Nature in November.

Scientists said next steps include trying to coax the synthetic mouse embryos to develop past 8 days with the eventual goal of getting them to term, which is 20 days for a mouse.

At this point, they struggle to go past the 8 1/2-day mark, said Gianluca Amadei, a coauthor on the Nature paper based at the University of Cambridge. We think that we will be able to get them over the hump, so to speak, so they can continue developing.

The scientists expect that after about 11 days of development the embryo will fail without a placenta, but they hope researchers can someday also find a way to create a synthetic placenta. At this point, they dont know if they will be able to get the synthetic embryos all the way to term without a mouse womb.

Researchers said they dont see creating human versions of these synthetic embryos soon but do see it happening in time. Hanna called it the next obvious thing.

Other scientists have already used human stem cells tocreate a blastoid, a structure mimicking a pre-embryo, that can serve as a research alternative to a real one.

Such work is subject to ethical concerns. For decades, a 14-day rule on growing embryos in the lab growing human embryos in the lab has guided researchers. Last year, the International Society for Stem Cell Research recommended relaxing the rule under limited circumstances.

Scientists stress that growing a baby from a synthetic human embryo is neither possible nor under consideration.

Perspective on this report is important since, without it, the headline that a mammalian embryo has been built in vitro can lead to the thought that the same can be done with humans soon, said developmental biologist Alfonso Martinez Arias of the Universitat Pompeu Fabra in Spain, whose group has developed alternative stem cell based models of animal development.

In the future, similar experiments will be done with human cells and that, at some point, will yield similar results, he said. This should encourage considerations of the ethics and societal impact of these experiments before they happen.

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Scientists use stem cells to create synthetic mouse embryos

Scientists Create Synthetic Mouse Embryos Using Stem Cells

Scientists have created synthetic mouse embryos from stem cells without a dads sperm or a moms egg or womb.

The lab-created embryos mirror a natural mouse embryo up to 8 days after fertilization, containing the same structures, including one like a beating heart.

A study published Thursday in the journal Nature, by Magdalena Zernicka-Goetz at the California Institute of Technology and her colleagues, was the latest to describe the synthetic mouse embryos. A similar study, by Jacob Hanna at the Weizmann Institute of Science in Israel and his colleagues, was published earlier this month in the journal Cell. Hanna was also a coauthor on the Nature paper.

Building embryo models is an alternative way to study these issues.

This is really the first model that allows you to study brain development in the context of the whole developing mouse embryo, she said.

Scientists said next steps include trying to coax the synthetic mouse embryos to develop past 8 days with the eventual goal of getting them to term, which is 20 days for a mouse.

Researchers said they dont see creating human versions of these synthetic embryos soon but do see it happening in time. Hanna called it the next obvious thing.

Other scientists have already used human stem cells to create a blastoid, a structure mimicking a pre-embryo, that can serve as a research alternative to a real one.

Such work is subject to ethical concerns. For decades, a 14-day rule on growing human embryos in the lab has guided researchers. Last year, the International Society for Stem Cell Research recommended relaxing the rule under limited circumstances.

Scientists stress that growing a baby from a synthetic human embryo is neither possible nor under consideration.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institutes Department of Science Education. The AP is solely responsible for all content.

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Scientists Create Synthetic Mouse Embryos Using Stem Cells